Diabetic neuropathy is a nerve disorder characterized by painful pins-and-needles sensations. Studies show that consuming linoleic acid may help to lower LDL cholesterol, improve blood pressure and reduce your overall risk of cardiovascular disease.

Treatment of Rheumatoid Arthritis with Marine and Botanical Oils: An 18-Month, Randomized, and Double-Blind Trial. Atopic dermatitis is one of the more common forms of eczema, alongside contact dermatitis and seborrheic dermatitis.
CLA: CLA, or conjugated linoleic acid, refers to a group of conjugated octadecadienoic acid isomers that are derived from linoleic acid. Due to its estrogen-like effects, GLA supplements should be avoided during pregnancy at they may increase the risk of miscarriage. When you eat an excessive amount of omega-6 foods, like products made from vegetable oils, it has a pro-inflammatory response. Classified as an omega-6 fatty acid, GLA is converted by the body into substances that fight inflammation and cell damage. Researchers concluded that these results indicate the acid’s potential beneficial role in the treatment of postmenopausal and menopause symptoms, including hot flashes, vaginal atrophy, reduced cardiovascular health and the development of osteoporosis. (10), Impaired reproductive health is a symptom of linoleic acid deficiency. Hemp seed oil, evening primrose oil, borage seed oil, and blackcurrant oil are among some of the highest sources of GLA.

So instead of focusing on the benefits of these polyunsaturated fatty acids, we usually hear about their pro-inflammatory properties when eaten in excess. (1), Linoleic acid is also an important structural component of cell membranes and affects cell membrane properties like fluidity, flexibility and permeability.


Keep the supplements away from direct sunlight, which can oxidize the fatty acids, and dispose of any gelcaps that are leaking or misshapen. Linoleic acid is a polyunsaturated essential fatty acid that is found mostly in plant oils. Alpha-linolenic acid might make the condition worse. (For a 100-pound woman, that would translate to roughly 550 milligrams per day. Animal studies indicate that this acid may be involved in neurotransmission and participates in the response to ischemic brain injury, such as stroke. Consumers are increasingly avoiding products that contain trans fats, and governments have begun to ban trans fats in food products.

Linoleic acid is the other essential fatty acid, but it, and the other n−6 fatty acids, compete with n−3s for positions in cell membranes and have very different effects on human health. Seed oils are the richest sources of α-linolenic acid, notably those of hempseed, chia, perilla, flaxseed (linseed oil), rapeseed (canola), and soybeans. Adv Ther. I should note that there have been studies indicating that linoleic acid does not reduce the development of heart disease, so a definitive conclusion about the benefits of linoleic acid for cardiovascular health isn’t possible at this time. The Benefits of Agaricus Mushrooms You Should Know, The influence of short-chain essential fatty acids on children with attention-deficit/hyperactivity disorder: a double-blind placebo-controlled study, Supplementary Health Benefits of Linoleic Acid by Improvement of Vaginal Cornification of Ovariectomized Rats, Treatment of Rheumatoid Arthritis with Marine and Botanical Oils: An 18-Month, Randomized, and Double-Blind Trial, Gamma-Linolenic Acid Levels Correlate with Clinical Efficacy of Evening Primrose Oil in Patients with Atopic Dermatitis. In the body, GLA is a precursor of a compound known as prostaglandin. This shouldn't suggest that everyone needs such high doses or that lower doses are any less effective than higher ones.